Assay Detail
Functional
CHEMBL994486
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Agonist activity at CB1 receptor expressed in mouse brain membrane by [35S]GTPgammaS binding assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Tissue | Brain |
| Subcellular | Membrane |
| Confidence | 9 — Direct single protein target |
| Curated By | Autocuration |
Publication
Conformationally constrained fatty acid ethanolamides as cannabinoid and vanilloid receptor probes.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| EC50 | 3 | 6.05 | 6.44 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL15848 | ANANDAMIDE | — | 1 | 6.44 |
| CHEMBL475904 | — | — | 1 | 6.11 |
| CHEMBL485369 | — | — | 1 | 5.59 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL15848 | ANANDAMIDE | EC50 | = | 360.0 | nM | 6.44 |
| CHEMBL475904 | — | EC50 | = | 780.0 | nM | 6.11 |
| CHEMBL485369 | — | EC50 | = | 2550.0 | nM | 5.59 |