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Assay Detail

CHEMBL994869

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Antiporter activity in Escherichia coli K12 wild type EcNhaA F72C mutant assessed as effect on lithium chloride-induced pH changes by acridine orange fluorescence assay
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Organism Escherichia coli
Confidence 1 — Organism
Curated By Autocuration

Publication

Model structure of the Na+/H+ exchanger 1 (NHE1): functional and clinical implications.
Landau M, Herz K, Padan E, Ben-Tal N.
J Biol Chem (2007) 282 : 37854 -37863
PubMed 17981808 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
IC50 1 5.58 5.58

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL311074 1 5.58

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL311074 IC50 = 2600.0 nM 5.58