Assay Detail
Functional
CHEMBL995250
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Antimicrobial activity against Staphylococcus aureus ATCC 6538
5
Total Activities
4
Compounds Tested
2
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Staphylococcus aureus |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Bioactive asterric acid derivatives from the Antarctic ascomycete fungus Geomyces sp.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 4.76 | 4.76 |
| MIC | 1 | - | - |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL507180 | GEOMYCIN C | — | 2 | 4.76 |
| CHEMBL499049 | ETHYL ASTERRATE | — | 1 | - |
| CHEMBL501396 | GEOMYCIN A | — | 1 | - |
| CHEMBL499873 | BUTYL ASTERRATE | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL507180 | GEOMYCIN C | IC50 | = | 17300.0 | nM | 4.76 |
| CHEMBL507180 | GEOMYCIN C | MIC | = | 75800.0 | nM | - |
| CHEMBL499049 | ETHYL ASTERRATE | IC50 | > | 50000.0 | nM | - |
| CHEMBL501396 | GEOMYCIN A | IC50 | > | 50000.0 | nM | - |
| CHEMBL499873 | BUTYL ASTERRATE | IC50 | > | 50000.0 | nM | - |