Assay Detail
Binding
CHEMBL995511
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of squalene synthase
4
Total Activities
4
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 8 — Homologous single protein target |
| Curated By | Intermediate |
Publication
Novel Zaragozic Acids from Leptodontidium elatius
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 4 | 9.08 | 9.70 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL507677 | — | — | 1 | 9.70 |
| CHEMBL505374 | ZARAGOZIC ACID C | — | 1 | 9.52 |
| CHEMBL445291 | ZARAGOZIC ACID F | — | 1 | 8.70 |
| CHEMBL508773 | ZARAGOZIC ACID E | — | 1 | 8.40 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL507677 | — | IC50 | = | 0.2 | nM | 9.70 |
| CHEMBL505374 | ZARAGOZIC ACID C | IC50 | = | 0.3 | nM | 9.52 |
| CHEMBL445291 | ZARAGOZIC ACID F | IC50 | = | 2.0 | nM | 8.70 |
| CHEMBL508773 | ZARAGOZIC ACID E | IC50 | = | 4.0 | nM | 8.40 |