Assay Detail
Functional
CHEMBL995943
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Cytotoxicity against human HL60 cells by MTS assay
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Cell Type | HL-60 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Discovery of novel Myc-Max heterodimer disruptors with a three-dimensional pharmacophore model.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 4.64 | 4.82 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL504747 | — | — | 1 | 4.82 |
| CHEMBL489096 | — | — | 1 | 4.64 |
| CHEMBL443375 | — | — | 1 | 4.46 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL504747 | — | IC50 | = | 15000.0 | nM | 4.82 |
| CHEMBL489096 | — | IC50 | = | 23000.0 | nM | 4.64 |
| CHEMBL443375 | — | IC50 | = | 35000.0 | nM | 4.46 |