Assay Detail
ADMET
CHEMBL997217
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Cytotoxicity against human BJ cells after 48 hrs by Alamar Blue assay
6
Total Activities
6
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Homo sapiens |
| Cell Type | BJ |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Efficient chemoenzymatic synthesis, cytotoxic evaluation, and SAR of epoxysterols.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 6 | 4.84 | 5.57 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | 4.0 | 1 | 5.57 |
| CHEMBL497835 | — | — | 1 | 4.87 |
| CHEMBL497816 | — | — | 1 | 4.71 |
| CHEMBL497834 | — | — | 1 | 4.70 |
| CHEMBL496805 | — | — | 1 | 4.69 |
| CHEMBL496407 | — | — | 1 | 4.50 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL53463 | DOXORUBICIN | IC50 | = | 2700.0 | nM | 5.57 |
| CHEMBL497835 | — | IC50 | = | 13400.0 | nM | 4.87 |
| CHEMBL497816 | — | IC50 | = | 19500.0 | nM | 4.71 |
| CHEMBL497834 | — | IC50 | = | 20100.0 | nM | 4.70 |
| CHEMBL496805 | — | IC50 | = | 20400.0 | nM | 4.69 |
| CHEMBL496407 | — | IC50 | = | 31400.0 | nM | 4.50 |