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Assay Detail

CHEMBL998018

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Functional
Agonist activity at androgen receptor assessed as receptor transactivation by reporter gene assay
2
Total Activities
1
Compounds Tested
2
Activity Types
0
Assay Parameters

Assay Information

Assay Type Functional
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

Androgen receptor (CHEMBL1871)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Nonsteroidal selective androgen receptor modulators (SARMs): dissociating the anabolic and androgenic activities of the androgen receptor for therapeutic benefit.
Mohler ML, Bohl CE, Jones A, Coss CC, Narayanan R, He Y, Hwang DJ, Dalton JT, Miller DD.
J Med Chem (2009) 52 : 3597 -3617
PubMed 19432422 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Activity 1 - -
EC50 1 8.52 8.52

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL390728 2 8.52

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL390728 EC50 = 3.0 nM 8.52
CHEMBL390728 Activity = 107.0 % -