Assay Detail
Functional
CHEMBL998404
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Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of LPS-induced nitrite accumulation after 24 hrs
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Mus musculus |
| Cell Type | RAW264.7 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Anti-inflammatory phloroglucinols and terpenoids from Garcinia subelliptica.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.00 | 5.54 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL107251 | 1400W | — | 1 | 5.54 |
| CHEMBL519681 | GARCINIELLIPTONE M | — | 1 | 4.82 |
| CHEMBL484649 | GARCINIELLIPTONE L | — | 1 | 4.64 |
| CHEMBL482802 | GARCINIELLIPTONE N | — | 1 | - |
| CHEMBL521127 | GARCINIELLIPTONE O | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL107251 | 1400W | IC50 | = | 2900.0 | nM | 5.54 |
| CHEMBL519681 | GARCINIELLIPTONE M | IC50 | = | 15300.0 | nM | 4.82 |
| CHEMBL484649 | GARCINIELLIPTONE L | IC50 | = | 22700.0 | nM | 4.64 |
| CHEMBL482802 | GARCINIELLIPTONE N | IC50 | > | 30000.0 | nM | - |
| CHEMBL521127 | GARCINIELLIPTONE O | IC50 | > | 30000.0 | nM | - |