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Assay Detail

CHEMBL998540

Review assay metadata, readout intent, target linkage, and publication context from the same page.

Binding
Binding affinity to neuromedin B receptor
1
Total Activities
1
Compounds Tested
1
Activity Types
0
Assay Parameters

Assay Information

Assay Type Binding
Confidence 8 — Homologous single protein target
Curated By Intermediate

Target

Neuromedin-B receptor (CHEMBL3636)
Type SINGLE PROTEIN
Organism Homo sapiens

Publication

Discovery of small molecule agonists for the bombesin receptor subtype 3 (BRS-3) based on an omeprazole lead.
Carlton DL, Collin-Smith LJ, Daniels AJ, Deaton DN, Goetz AS, Laudeman CP, Littleton TR, Musso DL, Morgan RJ, Szewczyk JR, Zhang C.
Bioorg Med Chem Lett (2008) 18 : 5451 -5455
PubMed 18818070 · DOI

Activity Statistics

Type Count Avg pChEMBL Best pChEMBL
Ki 1 8.05 8.05

Compounds Tested

Compound Name Phase Activities Best pChEMBL
CHEMBL525577 1 8.05

Activity Data

Compound Name Type Rel. Value Units pChEMBL
CHEMBL525577 Ki = 8.9 nM 8.05