Assay Detail
Functional
CHEMBL998655
Review assay metadata, readout intent, target linkage, and publication context from the same page.
Inhibition of TNFalpha production in human whole blood
2
Total Activities
2
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Tissue | Blood |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Current perspective of TACE inhibitors: a review.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 2 | 7.59 | 9.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL516978 | — | — | 1 | 9.38 |
| CHEMBL524092 | — | — | 1 | 5.80 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL516978 | — | IC50 | = | 0.42 | nM | 9.38 |
| CHEMBL524092 | — | IC50 | = | 1570.0 | nM | 5.80 |