Assay Detail
ADMET
CHEMBL998808
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Cytotoxicity against mouse 3T3 cells after 72 hrs by MTT assay
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | ADMET |
| Organism | Mus musculus |
| Cell Type | NIH3T3 |
| Confidence | 1 — Organism |
| Curated By | Autocuration |
Publication
Cycloartane triterpenoids from Astragalus bicuspis.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.01 | 6.04 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL123292 | CYCLOHEXIMIDE | 2.0 | 1 | 6.04 |
| CHEMBL500607 | — | — | 1 | 4.71 |
| CHEMBL450438 | — | — | 1 | 4.28 |
| CHEMBL501026 | — | — | 1 | - |
| CHEMBL504655 | — | — | 1 | - |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL123292 | CYCLOHEXIMIDE | IC50 | = | 912.0 | nM | 6.04 |
| CHEMBL500607 | — | IC50 | = | 19510.0 | nM | 4.71 |
| CHEMBL450438 | — | IC50 | = | 52380.0 | nM | 4.28 |
| CHEMBL501026 | — | IC50 | > | 100000.0 | nM | - |
| CHEMBL504655 | — | IC50 | > | 100000.0 | nM | - |