Assay Detail
Binding
CHEMBL999941
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Inhibition of calmodulin-dependent PDE1 activation
3
Total Activities
3
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Binding |
| Confidence | 0 — Uncurated / Unknown |
| Curated By | Autocuration |
Publication
Phytotoxins from Hofmeisteria schaffneri: isolation and synthesis of 2'-(2' '-hydroxy-4' '-methylphenyl)-2'-oxoethyl acetate1.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 3 | 5.30 | 5.38 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL486806 | — | — | 1 | 5.38 |
| CHEMBL446527 | HOFMEISTERIN | — | 1 | 5.36 |
| CHEMBL71 | CHLORPROMAZINE | 4.0 | 1 | 5.17 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL486806 | — | IC50 | = | 4200.0 | nM | 5.38 |
| CHEMBL446527 | HOFMEISTERIN | IC50 | = | 4400.0 | nM | 5.36 |
| CHEMBL71 | CHLORPROMAZINE | IC50 | = | 6800.0 | nM | 5.17 |