Compound Detail
CHEMBL446527
HOFMEISTERIN Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL446527 |
| Name | HOFMEISTERIN |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LHLJANTYAXQUPZ-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
208.2
MW (Da)
1.45
ALogP
4
HBA
1
HBD
63.6
PSA (Ų)
0.60
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.36
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 5.36 | 5.36 | 4400.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 4400.0 | nM | 5.36 | Inhibition of calmodulin-dependent PDE1 activation | 15974630 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15974630 | 10.1021/np0501278 | Amaranthus hypochondriacus | 1 |
| 15974630 | 10.1021/np0501278 | Echinochloa crus-galli | 1 |
| 15974630 | 10.1021/np0501278 | Medicago sativa | 1 |
| 15974630 | 10.1021/np0501278 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine