Compound Detail
CHEMBL104077
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
COc1cccc(-c2cn(-c3cccc(C(=O)Nc4ccc(C(P(=O)(O)O)P(=O)(O)O)cc4)c3)c3ncnc(N)c23)c1
Basic Information
| ChEMBL ID | CHEMBL104077 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | CEUUJOBSKLTCBL-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
609.5
MW (Da)
4.28
ALogP
8
HBA
6
HBD
210.1
PSA (Ų)
0.14
QED
2
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.72
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Proto-oncogene tyrosine-protein kinase Src CHEMBL267 | IC50 | 4.72 | 4.72 | 19000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Proto-oncogene tyrosine-protein kinase Src | IC50 | = | 19000.0 | nM | 4.72 | In vitro inhibition of Src protein tyrosine kinase using the Scintillation proxi... | 12941334 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 12941334 | 10.1016/s0960-894x(03)00647-4 | Proto-oncogene tyrosine-protein kinase Src | 1 |
Data from ChEMBL 36 via Core Engine