Compound Detail
CHEMBL105429
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Basic Information
| ChEMBL ID | CHEMBL105429 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GRPWUOMZDOTPOW-QNEBEIHSSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
363.6
MW (Da)
5.85
ALogP
2
HBA
2
HBD
49.3
PSA (Ų)
0.24
QED
1
Ro5 Violations
18
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.27
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Cannabinoid receptor CHEMBL2111415 | Ki | 7.27 | 7.27 | 53.4 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Cannabinoid receptor | Ki | = | 53.4 | nM | 7.27 | Ability to displace [3H]HU-243 binding to cannabinoid receptor in synaptosomal m... | 8411021 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8411021 | 10.1021/jm00072a026 | Cannabinoid receptor | 1 |
Data from ChEMBL 36 via Core Engine