Compound Detail
CHEMBL10763
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Basic Information
| ChEMBL ID | CHEMBL10763 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GOCZKPDHVLYWBI-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
384.5
MW (Da)
5.00
ALogP
4
HBA
2
HBD
53.2
PSA (Ų)
0.45
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.01
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Telomerase reverse transcriptase CHEMBL2916 | IC50 | 5.01 | 5.01 | 9800.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Telomerase reverse transcriptase | IC50 | = | 9800.0 | nM | 5.01 | Tested for inhibitory activity against Telomerase in telomerase repeat amplifica... | 11909720 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11909720 | 10.1016/s0960-894x(02)00080-x | Telomerase reverse transcriptase | 1 |
| 11909720 | 10.1016/s0960-894x(02)00080-x | DNA polymerase I, thermostable | 1 |
| - | 10.1007/s00044-011-9594-4 | Telomerase reverse transcriptase | 1 |
Data from ChEMBL 36 via Core Engine