Compound Detail
CHEMBL1076663
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
CNCC(=O)N[C@@H](CCCNC(=N)N)C(=O)N[C@H](C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc(C2(C(F)(F)F)N=N2)cc1)C(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccccc1)C(=O)O)C(C)C
Basic Information
| ChEMBL ID | CHEMBL1076663 |
| Phase | Preclinical |
| Structure Type | BOTH |
| InChI Key | SNWKXBZXLCHRMD-PSTHHSQNSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
1144.2
MW (Da)
Drug Information
| Molecule Type | Protein |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 9.3
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Type-1 angiotensin II receptor CHEMBL227 | Ki | 9.3 | 9.3 | 0.5 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Type-1 angiotensin II receptor | Ki | = | 0.5 | nM | 9.3 | Displacement of [125I][Sar1,Ile8]Ang2 from human AT1 receptor N111G constitutive... | 20146480 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 20146480 | 10.1021/jm9015747 | Type-1 angiotensin II receptor | 4 |
Data from ChEMBL 36 via Core Engine