Compound Detail
CHEMBL1080239
LINDERALACTONE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL1080239 |
| Name | LINDERALACTONE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LWCKQMHMTSRRAA-QGQQYVBWSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
244.3
MW (Da)
3.39
ALogP
3
HBA
0
HBD
39.4
PSA (Ų)
0.52
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 4.01
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| HepG2 CHEMBL395 | EC50 | 4.01 | 4.01 | 98000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| HepG2 | EC50 | = | 98000.0 | nM | 4.01 | Hepatoprotective activity in human HepG2 cells assessed as inhibition of H2O2- i... | 19639966 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 22148193 | 10.1021/np100874f | NON-PROTEIN TARGET | 2 |
| 19639966 | 10.1021/np900354q | HepG2 | 1 |
Data from ChEMBL 36 via Core Engine