Compound Detail
CHEMBL1085765
MECLIZINE DIHCL Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL1085765 |
| Name | MECLIZINE DIHCL |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GJNMJOHYRWHJQB-UHFFFAOYSA-N |
| Parent Compound | CHEMBL1623 |
| Active Moiety | CHEMBL1623 |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
391.0
MW (Da)
5.56
ALogP
2
HBA
0
HBD
6.5
PSA (Ų)
0.56
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 4.79
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 4.79 | 4.79 | 16323.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 16323.0 | nM | 4.79 | PUBCHEM_BIOASSAY: High Throughput Screen to Identify Inhibitors of Mycobacterium... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 20426472 | 10.1021/jm100254w | Cruzipain | 2 |
| 20426472 | 10.1021/jm100254w | No relevant target | 2 |
Data from ChEMBL 36 via Core Engine