Compound Detail
CHEMBL1089034
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1089034 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DBRCZHBYEHAPJF-GOSISDBHSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
411.4
MW (Da)
4.09
ALogP
4
HBA
2
HBD
83.6
PSA (Ų)
0.52
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.07
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 CHEMBL2288 | Ki | 5.07 | 5.07 | 8500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | Ki | = | 8500.0 | nM | 5.07 | Displacement of WFYpSPFLE from human Pin1 catalytic domain after 10-20 mins by f... | 20207139 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 20207139 | 10.1016/j.bmcl.2010.02.033 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 2 |
Data from ChEMBL 36 via Core Engine