Compound Detail
CHEMBL1095899
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Basic Information
| ChEMBL ID | CHEMBL1095899 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | JNXOQTZXOHWPCJ-LFUTUZGBSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
248.3
MW (Da)
2.50
ALogP
3
HBA
0
HBD
43.4
PSA (Ų)
0.62
QED
0
Ro5 Violations
0
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.89
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| RAW264.7 CHEMBL612557 | IC50 | 6.89 | 6.89 | 130.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| RAW264.7 | IC50 | = | 130.0 | nM | 6.89 | Antiinflammatory activity against mouse RAW264.7 cells assessed as inhibition of... | 20192236 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 20192236 | 10.1021/np9005053 | RAW264.7 | 1 |
Data from ChEMBL 36 via Core Engine