Compound Detail
CHEMBL109630
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Basic Information
| ChEMBL ID | CHEMBL109630 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | WAXUSWRZNQYUAJ-UJBXMFPWSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
410.6
MW (Da)
5.63
ALogP
5
HBA
1
HBD
72.8
PSA (Ų)
0.19
QED
1
Ro5 Violations
17
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 8.76
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Protein kinase C alpha type CHEMBL299 | Ki | 8.76 | 7.255 | 1.8 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Protein kinase C alpha type | Ki | = | 1.758 | nM | 8.76 | Affinity for protein kinase C alpha | 10966739 |
| Protein kinase C alpha type | Ki | = | 1758.0 | nM | 5.75 | Affinity for protein kinase-C alpha (PK-C alpha) | 10966739 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 10966739 | 10.1021/jm990613q | Protein kinase C alpha type | 2 |
Data from ChEMBL 36 via Core Engine