Compound Detail
CHEMBL110026
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Basic Information
| ChEMBL ID | CHEMBL110026 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | IBIOBBJOSFKEEH-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
371.5
MW (Da)
5.11
ALogP
2
HBA
3
HBD
79.0
PSA (Ų)
0.43
QED
1
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 6.78
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Urokinase-type plasminogen activator CHEMBL3286 | Ki | 6.78 | 6.78 | 167.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Urokinase-type plasminogen activator | Ki | = | 167.0 | nM | 6.78 | Binding affinity to human urokinase-type plasminogen activator (microPa). | 14711304 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 14711304 | 10.1021/jm0300072 | Urokinase-type plasminogen activator | 1 |
Data from ChEMBL 36 via Core Engine