Compound Detail
CHEMBL113381
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Basic Information
| ChEMBL ID | CHEMBL113381 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | YZOKHYPIQNIFRQ-UHFFFAOYSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
423.3
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 2 meas. best 7.1
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Beta-lactamase CHEMBL2026 | Ki | 7.1 | 7.1 | 80.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Beta-lactamase | Ki | = | 80.0 | nM | 7.1 | Binding affinity towards AmpC beta-lactamase binding site from Escherichia coli | 12109906 |
| Beta-lactamase | Ki | = | 80.0 | nM | 7.1 | Apparent inhibition constant against Escherichia coli AmpC beta-lactamase | 15225711 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 12109906 | 10.1021/jm020002p | Beta-lactamase | 1 |
| 15225711 | 10.1016/j.bmcl.2004.05.054 | Beta-lactamase | 1 |
Data from ChEMBL 36 via Core Engine