Compound Detail
CHEMBL114648
BETA-NAPHTOIC ACID Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL114648 |
| Name | BETA-NAPHTOIC ACID |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UOBYKYZJUGYBDK-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
12
Publications
0
Known Names
Molecular Properties
172.2
MW (Da)
2.54
ALogP
1
HBA
1
HBD
37.3
PSA (Ų)
0.72
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.21
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 4.21 | 4.21 | 61400.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 61400.0 | nM | 4.21 | Antagonist activity at Gloeobacter violaceus ligand-gated ion channel expressed ... | 23682762 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23682762 | 10.1021/jm400374q | Unchecked | 2 |
| 24499135 | 10.1021/jm401808n | Staphylococcus aureus | 2 |
| 671456 | 10.1021/jm00204a015 | Rattus norvegicus | 2 |
| 1527790 | 10.1021/jm00096a014 | No relevant target | 1 |
| 1527790 | 10.1021/jm00096a014 | ADMET | 1 |
| 3820229 | 10.1021/jm00386a022 | Polyunsaturated fatty acid 5-lipoxygenase | 1 |
| 23136941 | 10.1021/jf3038874 | Meloidogyne incognita | 1 |
| 23682762 | 10.1021/jm400374q | No relevant target | 1 |
| 24249037 | 10.1007/s11095-013-1232-z | No relevant target | 1 |
| 24499135 | 10.1021/jm401808n | Quinolone resistance protein NorA | 1 |
| 915902 | 10.1021/jm00221a013 | Unchecked | 1 |
| 26154240 | 10.1016/j.bmc.2015.06.042 | Curvularia lunata | 1 |
Data from ChEMBL 36 via Core Engine