Compound Detail
CHEMBL1159506
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
NCC1OC(OC2C(N)CC(N)C(O)C2OC2OC(CO)C(OC3OC(CN)C(O)C(O)C3O)C2O)C(N)C(O)C1O
Basic Information
| ChEMBL ID | CHEMBL1159506 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HTGNYGXWPSCVJB-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
615.6
MW (Da)
-8.86
ALogP
19
HBA
13
HBD
347.3
PSA (Ų)
0.11
QED
3
Ro5 Violations
9
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 6.16
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Ribosomal RNA A-site CHEMBL614640 | Kd | 6.16 | 6.16 | 700.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Ribosomal RNA A-site | Kd | = | 700.0 | nM | 6.16 | Binding affinity of aminoglycoside to 16S ribosomal RNA A-site in Escherichia co... | 11206440 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11206440 | 10.1016/s0960-894x(00)00615-6 | Ribosomal RNA A-site | 1 |
Data from ChEMBL 36 via Core Engine