Compound Detail
CHEMBL1159782
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Basic Information
| ChEMBL ID | CHEMBL1159782 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZWMWMFQYDLHNHO-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
481.6
MW (Da)
-6.05
ALogP
14
HBA
10
HBD
268.2
PSA (Ų)
0.15
QED
2
Ro5 Violations
8
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Kd 1 meas. best 5.77
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Ribosomal RNA A-site CHEMBL614640 | Kd | 5.77 | 5.77 | 1700.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Ribosomal RNA A-site | Kd | = | 1700.0 | nM | 5.77 | Binding affinity of aminoglycoside to 16S ribosomal RNA A-site in Escherichia co... | 11206440 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11206440 | 10.1016/s0960-894x(00)00615-6 | Ribosomal RNA A-site | 1 |
Data from ChEMBL 36 via Core Engine