Compound Detail
CHEMBL1160549
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL1160549 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | OOTOSDGHYXSFOS-BSQJROMVSA-N |
| Parent Compound | CHEMBL1199693 |
| Active Moiety | CHEMBL1199693 |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
263.3
MW (Da)
-2.70
ALogP
7
HBA
7
HBD
117.0
PSA (Ų)
0.26
QED
1
Ro5 Violations
6
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.55
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Tissue alpha-L-fucosidase CHEMBL4176 | Ki | 5.55 | 5.55 | 2800.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Tissue alpha-L-fucosidase | Ki | = | 2800.0 | nM | 5.55 | In vitro inhibition of alpha-L-fucosidase isolated from bovine kidney. | 11549468 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11549468 | 10.1016/s0960-894x(01)00497-8 | Tissue alpha-L-fucosidase | 1 |
Data from ChEMBL 36 via Core Engine