Skip to main content
Free research Free research Free compound review with research home and workspace preview
Quick search ChEMBL 36
Compound Detail

CHEMBL1161979

Enter ChEMBL ID:
Free Research Context This compound will appear in recent viewed items on the research home for this browser.
Research home View demo workspace
CN(C(=O)CCc1ccc(O)cc1)[C@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCC(N)=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](CCCNC(=N)N)C(=O)N1CC[C@H](C(=O)N(C(=O)c2ccc(-c3c4ccc(=N)c(S(=O)(=O)O)c-4oc4c(S(=O)(=O)O)c(N)ccc34)c(C(=O)O)c2)[C@@H](CCCCN)C(N)=O)C1

Basic Information

ChEMBL ID CHEMBL1161979
Phase Preclinical
Structure Type MOL
InChI Key JTPJNKPWLHDAAT-RHFIIQKYSA-N
2
Targets
2
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names

Molecular Properties

1629.8
MW (Da)

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

First in Class Prodrug

Extended Properties

Molecular Formula C75H88N16O22S2
MW 1629.75

Activity Summary

Ki 2 meas. best 8.71

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Oxytocin receptor
CHEMBL2049
Ki 8.71 8.71 1.9 1
Vasopressin V1a receptor
CHEMBL1889
Ki 8.68 8.68 2.1 1

Activity Data Samples

Top measurements by pChEMBL value

Literature References

PubMed DOI Target Context # Activities
17850055 10.1021/jm061404q Vasopressin V1a receptor 3
17850055 10.1021/jm061404q Oxytocin receptor 3
17850055 10.1021/jm061404q Vasopressin V1b receptor 1
17850055 10.1021/jm061404q Vasopressin V2 receptor 1

Data from ChEMBL 36 via Core Engine