Compound Detail
CHEMBL116266
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL116266 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RPJMKIJTRRYIHC-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
253.2
MW (Da)
1.08
ALogP
6
HBA
2
HBD
126.5
PSA (Ų)
0.61
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 5.7
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate receptor ionotropic, AMPA CHEMBL2093871 | Ki | 5.7 | 5.7 | 2000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate receptor ionotropic, AMPA | Ki | = | 2000.0 | nM | 5.7 | Binding affinity for ionotropic glutamate receptor AMPA using [3H]AMPA as radiol... | 14505662 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 14505662 | 10.1016/s0960-894x(03)00740-6 | Glutamate receptor ionotropic, AMPA | 1 |
Data from ChEMBL 36 via Core Engine