Compound Detail
CHEMBL1172893
GALANTHINE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL1172893 |
| Name | GALANTHINE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | VOIMPDXOQJYVDI-WNRNVDISSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
16
Publications
0
Known Names
Molecular Properties
317.4
MW (Da)
1.69
ALogP
5
HBA
1
HBD
51.2
PSA (Ų)
0.86
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.21
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Acetylcholinesterase CHEMBL220 | IC50 | 5.21 | 5.21 | 6100.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Acetylcholinesterase | IC50 | = | 6100.0 | nM | 5.21 | Inhibition of AChE (unknown origin) | 28898076 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 20550100 | 10.1021/np9008255 | NON-PROTEIN TARGET | 3 |
| 20550100 | 10.1021/np9008255 | A549 | 1 |
| 20550100 | 10.1021/np9008255 | SK-MEL | 1 |
| 20550100 | 10.1021/np9008255 | B16-F10 | 1 |
| 28898076 | 10.1021/acs.jnatprod.7b00301 | Acetylcholinesterase | 1 |
| 31515186 | 10.1016/j.bmcl.2019.126642 | Trypanosoma brucei rhodesiense | 1 |
| 39229678 | 10.1021/acs.jnatprod.4c00825 | Jurkat | 1 |
| 39229678 | 10.1021/acs.jnatprod.4c00825 | MOLT-4 | 1 |
| 39229678 | 10.1021/acs.jnatprod.4c00825 | A549 | 1 |
| 39229678 | 10.1021/acs.jnatprod.4c00825 | HT-29 | 1 |
| 39229678 | 10.1021/acs.jnatprod.4c00825 | PANC-1 | 1 |
| 39229678 | 10.1021/acs.jnatprod.4c00825 | A2780 | 1 |
| 39229678 | 10.1021/acs.jnatprod.4c00825 | HeLa | 1 |
| 39229678 | 10.1021/acs.jnatprod.4c00825 | MCF7 | 1 |
| 39229678 | 10.1021/acs.jnatprod.4c00825 | SAOS-2 | 1 |
| 39229678 | 10.1021/acs.jnatprod.4c00825 | MRC5 | 1 |
Data from ChEMBL 36 via Core Engine