Compound Detail
CHEMBL1189513
FURALTADONE 🧪 Phase II
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
🧪 Phase II
Basic Information
| ChEMBL ID | CHEMBL1189513 |
| Name | FURALTADONE |
| Phase | Phase II |
| Structure Type | MOL |
| InChI Key | YVQVOQKFMFRVGR-VGOFMYFVSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
12
Publications
4
Known Names
Molecular Properties
324.3
MW (Da)
0.67
ALogP
8
HBA
0
HBD
110.7
PSA (Ų)
0.44
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Chirality | Racemic |
Activity Summary
IC50 1 meas. best 4.87
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Mitogen-activated protein kinase 9 CHEMBL4179 | IC50 | 4.87 | 4.87 | 13500.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Mitogen-activated protein kinase 9 | IC50 | = | 13500.0 | nM | 4.87 | Inhibition of human JNK2alpha2 using GST-c-jun (1 to 221) as substrate preincuba... | 23002419 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23002419 | 10.1021/ml300129b | Mitogen-activated protein kinase 9 | 3 |
| 27687671 | 10.1016/j.bmcl.2016.09.009 | CDGSH iron-sulfur domain-containing protein 1 | 2 |
| - | 10.6019/CHEMBL4495565 | SARS-CoV-2 | 2 |
| - | 10.6019/CHEMBL4651402 | SARS-CoV-2 | 2 |
| - | 10.6019/CHEMBL4808148 | Histone deacetylase 6 | 2 |
| 23002419 | 10.1021/ml300129b | Mitogen-activated protein kinase 14 | 1 |
| 23002419 | 10.1021/ml300129b | Mitogen-activated protein kinase 1 | 1 |
| - | 10.21203/rs.3.rs-23951/v1 | SARS-CoV-2 | 1 |
| - | 10.1101/2020.04.21.054387 | SARS-CoV-2 | 1 |
| - | 10.6019/CHEMBL4495564 | Replicase polyprotein 1ab | 1 |
| 36940609 | 10.1016/j.bmc.2023.117239 | Chikungunya virus | 1 |
| 38318365 | 10.1016/j.isci.2024.108907 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 1 |
Data from ChEMBL 36 via Core Engine