Compound Detail
CHEMBL120198
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Basic Information
| ChEMBL ID | CHEMBL120198 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HLFIMQPMHNUTJR-GDNBJRDFSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
366.4
MW (Da)
3.26
ALogP
4
HBA
4
HBD
126.6
PSA (Ų)
0.33
QED
0
Ro5 Violations
7
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 6.82
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Dipeptidase 1 CHEMBL1989 | IC50 | 6.82 | 6.82 | 150.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Dipeptidase 1 | IC50 | = | 150.0 | nM | 6.82 | Concentration required to inhibit renal dipeptidase (RDP) by 50% in crude lysate... | 15177467 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 15177467 | 10.1016/j.bmcl.2004.04.057 | Dipeptidase 1 | 1 |
Data from ChEMBL 36 via Core Engine