Compound Detail
CHEMBL1205735
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Basic Information
| ChEMBL ID | CHEMBL1205735 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | GAJHFPYRNGGGFX-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
198.2
MW (Da)
-0.86
ALogP
5
HBA
3
HBD
109.5
PSA (Ų)
0.42
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 5.0
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Glutamate [NMDA] receptor CHEMBL2094124 | IC50 | 5.0 | 5.0 | 10000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Glutamate [NMDA] receptor | IC50 | = | 10000.0 | nM | 5.0 | Antagonist activity at NMDA receptor (unknwon origin) | 21413808 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 21413808 | 10.1021/jm1013693 | Glutamate [NMDA] receptor | 1 |
Data from ChEMBL 36 via Core Engine