Assay Detail
Functional
CHEMBL2208698
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Antagonist activity at NMDA receptor (unknwon origin)
5
Total Activities
5
Compounds Tested
1
Activity Types
0
Assay Parameters
Assay Information
| Assay Type | Functional |
| Organism | Homo sapiens |
| Confidence | 5 — Multiple protein complex / RNA |
| Curated By | Autocuration |
Publication
Synopsis of some recent tactical application of bioisosteres in drug design.
Activity Statistics
| Type | Count | Avg pChEMBL | Best pChEMBL |
|---|---|---|---|
| IC50 | 5 | 5.99 | 7.16 |
Compounds Tested
| Compound | Name | Phase | Activities | Best pChEMBL |
|---|---|---|---|---|
| CHEMBL575060 | GLUTAMIC ACID | 3.0 | 1 | 7.16 |
| CHEMBL145806 | — | — | 1 | 6.33 |
| CHEMBL1207193 | — | — | 1 | 5.80 |
| CHEMBL1205743 | — | — | 1 | 5.64 |
| CHEMBL1205735 | — | — | 1 | 5.00 |
Activity Data
| Compound | Name | Type | Rel. | Value | Units | pChEMBL |
|---|---|---|---|---|---|---|
| CHEMBL575060 | GLUTAMIC ACID | IC50 | = | 70.0 | nM | 7.16 |
| CHEMBL145806 | — | IC50 | = | 470.0 | nM | 6.33 |
| CHEMBL1207193 | — | IC50 | = | 1600.0 | nM | 5.80 |
| CHEMBL1205743 | — | IC50 | = | 2300.0 | nM | 5.64 |
| CHEMBL1205735 | — | IC50 | = | 10000.0 | nM | 5.00 |