Compound Detail
CHEMBL1213178
ALLOPURINOL RIBOSIDE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL1213178 |
| Name | ALLOPURINOL RIBOSIDE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UKNHQPDCWMADJW-QFNGTQGLSA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
4
Publications
0
Known Names
Molecular Properties
268.2
MW (Da)
-2.32
ALogP
8
HBA
4
HBD
133.5
PSA (Ų)
0.48
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 5.4
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Leishmania donovani CHEMBL367 | IC50 | 5.4 | 5.4 | 4000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Leishmania donovani | IC50 | = | 4000.0 | nM | 5.4 | Antimicrobial activity against Leishmania donovani | 20185316 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 20921305 | 10.1128/aac.01029-10 | Bacillus anthracis | 2 |
| 20185316 | 10.1016/j.bmc.2010.01.068 | Leishmania donovani | 1 |
| 20921305 | 10.1128/aac.01029-10 | J774.A1 | 1 |
| - | 10.1101/2020.04.21.054387 | SARS-CoV-2 | 1 |
Data from ChEMBL 36 via Core Engine