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Compound Detail

CHEMBL1213876

CINNAMTANNIN D1
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Oc1cc(O)c2c(c1)O[C@@]1(c3ccc(O)c(O)c3)Oc3cc(O)c4c(c3[C@@H]2[C@H]1O)O[C@H](c1ccc(O)c(O)c1)[C@H](O)[C@H]4c1c(O)cc(O)c2c1O[C@H](c1ccc(O)c(O)c1)[C@@H](O)C2

Basic Information

ChEMBL ID CHEMBL1213876
Name CINNAMTANNIN D1
Phase Preclinical
Structure Type MOL
InChI Key BYSRPHRKESMCPO-HMQYECKYSA-N
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names

Molecular Properties

864.8
MW (Da)
4.24
ALogP
18
HBA
14
HBD
320.1
PSA (Ų)
0.11
QED
3
Ro5 Violations
4
Rot. Bonds

Drug Information

Molecule Type Small molecule
Availability Unknown
Chirality Unknown

Flags

Natural Product First in Class Prodrug

Extended Properties

Molecular Formula C45H36O18
MW 864.77
Aromatic Rings 6
Heavy Atoms 63
NP-Likeness 1.74

Activity Summary

IC50 1 meas. best 4.03

Target Activity Profile

Target Type Best pChEMBL Mean pChEMBL Best (nM) # Data
Unchecked
CHEMBL612545
IC50 4.03 4.03 92900.0 1

Activity Data Samples

Top measurements by pChEMBL value

Target Type Rel. Value Units pChEMBL Assay PubMed
Unchecked IC50 = 92900.0 nM 4.03 Inhibition of Bacillus stearothermophilus alpha glucosidase-4 20568785

Literature References

PubMed DOI Target Context # Activities
21875098 10.1021/np1007944 Prostaglandin G/H synthase 2 3
20568785 10.1021/np1002274 Unchecked 1

Data from ChEMBL 36 via Core Engine