Compound Detail
CHEMBL121730
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Basic Information
| ChEMBL ID | CHEMBL121730 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BBRZZCYVWKZJJY-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
1
Publications
0
Known Names
Molecular Properties
415.6
MW (Da)
6.50
ALogP
3
HBA
2
HBD
58.6
PSA (Ų)
0.24
QED
1
Ro5 Violations
16
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 7.9
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Transient receptor potential cation channel subfamily V member 1 CHEMBL4794 | EC50 | 7.9 | 7.9 | 12.6 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Transient receptor potential cation channel subfamily V member 1 | EC50 | = | 12.59 | nM | 7.9 | Concentration necessary to induce a relative half-maximal response measured by t... | 12166946 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 12166946 | 10.1021/jm020844o | Transient receptor potential cation channel subfamily V member 1 | 2 |
Data from ChEMBL 36 via Core Engine