Compound Detail
CHEMBL122024
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL122024 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | LJADKHFBAHDMDH-UHFFFAOYSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
332.4
MW (Da)
4.13
ALogP
5
HBA
0
HBD
57.3
PSA (Ų)
0.53
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 3 meas. best 6.05
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 6.05 | 5.07 | 900.0 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 900.0 | nM | 6.05 | Inhibition of hypoxia-induced HIF-1 transcriptional activity by luciferase repor... | 21937231 |
| Unchecked | IC50 | = | 81100.0 | nM | 4.09 | Inhibition of platelet aggregation induced by AA (100 uM) | 11606139 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11606139 | 10.1021/jm010001h | Unchecked | 4 |
| 12408703 | 10.1021/jm020070b | Rattus norvegicus | 1 |
| 21937231 | 10.1016/j.bmcl.2011.08.120 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine