Compound Detail
CHEMBL1234751
ACETYLGLUTAMIC ACID Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL1234751 |
| Name | ACETYLGLUTAMIC ACID |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RFMMMVDNIPUKGG-YFKPBYRVSA-N |
2
Targets
2
Activities
2
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
189.2
MW (Da)
-0.56
ALogP
3
HBA
3
HBD
103.7
PSA (Ų)
0.54
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 9.64
IC50 1 meas. best 2.68
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Olfactory receptor 51E2 CHEMBL4523454 | EC50 | 9.64 | 9.64 | 0.2 | 1 |
| Lysine-specific demethylase 4C CHEMBL6175 | IC50 | 2.68 | 2.68 | 2070000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Olfactory receptor 51E2 | EC50 | = | 0.23 | nM | 9.64 | Agonist activity at PSGR/OR51E2 (unknown origin) expressed in human Hana3A cells... | - |
| Lysine-specific demethylase 4C | IC50 | = | 2070000.0 | nM | 2.68 | Inhibition of N-terminal His6-tagged KDM4C (1 to 352 residues) (unknown origin) ... | 26699912 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 23571415 | 10.1124/mol.112.084152 | Solute carrier organic anion transporter family member 1B3 | 1 |
| 23571415 | 10.1124/mol.112.084152 | Solute carrier organic anion transporter family member 1B1 | 1 |
| 26699912 | 10.1021/acs.jmedchem.5b01527 | Lysine-specific demethylase 4C | 1 |
Data from ChEMBL 36 via Core Engine