Compound Detail
CHEMBL1235228
PHOSPHOENOLPYRUVATE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL1235228 |
| Name | PHOSPHOENOLPYRUVATE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DTBNBXWJWCWCIK-UHFFFAOYSA-N |
1
Targets
4
Activities
1
Assay Types
0
PK Parameters
6
Publications
0
Known Names
Molecular Properties
168.0
MW (Da)
-0.31
ALogP
3
HBA
3
HBD
104.1
PSA (Ų)
0.30
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 4 meas. best 8.07
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Xaa-Pro dipeptidase CHEMBL4185 | Ki | 8.07 | 7.295 | 8.5 | 2 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Xaa-Pro dipeptidase | Ki | = | 8.5 | nM | 8.07 | Inhibition of prolidase from swine kidney at a pH 6 | - |
| Xaa-Pro dipeptidase | Ki | = | 300.0 | nM | 6.52 | Inhibitory constant for inhibition of prolidase in the first phase of biphasic i... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1016/0960-894X(95)00085-8 | Xaa-Pro dipeptidase | 3 |
| - | 10.6019/CHEMBL4495565 | SARS-CoV-2 | 2 |
| - | 10.1016/0960-894X(95)00085-8 | Unchecked | 1 |
| 11997326 | 10.1152/ajprenal.00151.2001 | Solute carrier organic anion transporter family member 2A1 | 1 |
| - | 10.6019/CHEMBL4495564 | Replicase polyprotein 1ab | 1 |
| 38128237 | 10.1016/j.ejmech.2023.116058 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine