Compound Detail
CHEMBL1236642
VACCENIC ACID Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL1236642 |
| Name | VACCENIC ACID |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UWHZIFQPPBDJPM-FPLPWBNLSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
282.5
MW (Da)
6.11
ALogP
1
HBA
1
HBD
37.3
PSA (Ų)
0.29
QED
1
Ro5 Violations
15
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 4.8
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Telomerase reverse transcriptase CHEMBL2916 | IC50 | 4.8 | 4.8 | 16000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Telomerase reverse transcriptase | IC50 | = | 16000.0 | nM | 4.8 | Inhibition of telomerase extracted from human K562 cells preincubated for 10 min... | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| - | 10.1039/C0MD00241K | Telomerase reverse transcriptase | 1 |
| 28704049 | 10.1021/acs.jnatprod.6b00823 | Albumin | 1 |
Data from ChEMBL 36 via Core Engine