Compound Detail
CHEMBL123708
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Basic Information
| ChEMBL ID | CHEMBL123708 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | AMSXTZUCNOKUEN-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
5
Publications
0
Known Names
Molecular Properties
259.4
MW (Da)
4.04
ALogP
2
HBA
1
HBD
23.5
PSA (Ų)
0.87
QED
0
Ro5 Violations
2
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
Ki 1 meas. best 7.42
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | Ki | 7.42 | 7.42 | 38.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | Ki | = | 38.0 | nM | 7.42 | Binding affinity against PCP site of the NMDA Receptor using [3H]TCP radioligand | - |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 6279847 | 10.1021/jm00346a019 | Glutamate receptor ionotropic, NMDA 2C | 2 |
| 6279847 | 10.1021/jm00346a019 | Muscarinic acetylcholine receptor | 2 |
| 6279847 | 10.1021/jm00346a019 | Opioid receptor | 2 |
| 6279847 | 10.1021/jm00346a019 | Mus musculus | 1 |
| - | 10.1016/0960-894X(95)00038-U | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine