Compound Detail
CHEMBL124181
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL124181 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HDUUCQLNBZTNGH-UHFFFAOYSA-N |
1
Targets
6
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
346.4
MW (Da)
4.44
ALogP
5
HBA
0
HBD
57.3
PSA (Ų)
0.51
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 6 meas. best 4.49
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | IC50 | 4.49 | 4.228 | 32400.0 | 5 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | IC50 | = | 32400.0 | nM | 4.49 | Inhibition of arachidonic acid-induced platelet aggregation in human platelet-ri... | 33049608 |
| Unchecked | IC50 | = | 59300.0 | nM | 4.23 | Inhibition of collagen-induced platelet aggregation in human platelet-rich plasm... | 33049608 |
| Unchecked | IC50 | = | 64200.0 | nM | 4.19 | Inhibition of platelet aggregation induced by AA (100 uM) | 11606139 |
| Unchecked | IC50 | = | 76300.0 | nM | 4.12 | Inhibition of PAF-induced platelet aggregation in human platelet-rich plasma inc... | 33049608 |
| Unchecked | IC50 | = | 78300.0 | nM | 4.11 | Inhibition of platelet aggregation induced by Collagen (10 uM) | 11606139 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 11606139 | 10.1021/jm010001h | Unchecked | 4 |
| 33049608 | 10.1016/j.ejmech.2020.112893 | Unchecked | 4 |
Data from ChEMBL 36 via Core Engine