Compound Detail
CHEMBL124905
Enter ChEMBL ID:
Free Research Context
This compound will appear in recent viewed items on the research home for this browser.
Research home
View demo workspace
Basic Information
| ChEMBL ID | CHEMBL124905 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | ZOTJAVXQUIZQEQ-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
456.5
MW (Da)
4.55
ALogP
4
HBA
1
HBD
71.8
PSA (Ų)
0.38
QED
0
Ro5 Violations
10
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 1 meas. best 7.52
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Leukotriene B4 receptor CHEMBL2095160 | IC50 | 7.52 | 7.52 | 30.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Leukotriene B4 receptor | IC50 | = | 30.0 | nM | 7.52 | LTB4 receptor binding from radioligand binding assay using guinea pig spleen cel... | 8809164 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 8809164 | 10.1021/jm950699x | Leukotriene B4 receptor | 1 |
| 8809164 | 10.1021/jm950699x | Leukotriene B4 receptor 1 | 1 |
Data from ChEMBL 36 via Core Engine