Compound Detail
CHEMBL12571
HYDROXYGUANIDINE SULPHATE Enter ChEMBL ID:
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Basic Information
| ChEMBL ID | CHEMBL12571 |
| Name | HYDROXYGUANIDINE SULPHATE |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | HADHZJGGNKXUCP-RJRFIUFISA-N |
1
Targets
2
Activities
1
Assay Types
0
PK Parameters
2
Publications
0
Known Names
Molecular Properties
198.2
MW (Da)
-1.96
ALogP
6
HBA
4
HBD
146.6
PSA (Ų)
0.14
QED
0
Ro5 Violations
3
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
IC50 2 meas. best 4.78
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| L1210 CHEMBL386 | IC50 | 4.78 | 4.78 | 16595.9 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| L1210 | IC50 | = | 16595.87 | nM | 4.78 | Concentration required for 50% inhibition of cell growth (L1210 Leukemia) | 2991520 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 2991520 | 10.1021/jm00146a022 | Rous sarcoma virus | 4 |
| 2991520 | 10.1021/jm00146a022 | L1210 | 2 |
Data from ChEMBL 36 via Core Engine