Compound Detail
CHEMBL1258409
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Basic Information
| ChEMBL ID | CHEMBL1258409 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | UHVGXSURQLRQLL-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
3
Publications
0
Known Names
Molecular Properties
419.8
MW (Da)
4.98
ALogP
6
HBA
2
HBD
103.7
PSA (Ų)
0.48
QED
0
Ro5 Violations
4
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 6.05
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Hepatitis C virus CHEMBL379 | EC50 | 6.05 | 6.05 | 900.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Hepatitis C virus | EC50 | = | 900.0 | nM | 6.05 | Antiviral activity against HCV assessed as inhibition of viral replication by lu... | 20797857 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 20797857 | 10.1016/j.bmcl.2010.08.012 | Hepatitis C virus | 1 |
| 20797857 | 10.1016/j.bmcl.2010.08.012 | ADMET | 1 |
| 20797857 | 10.1016/j.bmcl.2010.08.012 | Unchecked | 1 |
Data from ChEMBL 36 via Core Engine