Compound Detail
CHEMBL127096
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Basic Information
| ChEMBL ID | CHEMBL127096 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | DTELDBUFGPSBQS-WDSKDSINSA-N |
1
Targets
3
Activities
1
Assay Types
0
PK Parameters
8
Publications
0
Known Names
Molecular Properties
294.1
MW (Da)
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 3 meas. best 5.19
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Human immunodeficiency virus 1 CHEMBL378 | EC50 | 5.19 | 4.4833 | 6400.0 | 3 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Human immunodeficiency virus 1 | EC50 | = | 6400.0 | nM | 5.19 | Antiviral activity against Immunodeficiency virus type-1 (HIV-1) in peripheral b... | 11052795 |
| Human immunodeficiency virus 1 | EC50 | = | 57100.0 | nM | 4.24 | Antiviral activity against Immunodeficiency virus type-1 (HIV-1) in peripheral b... | 11052795 |
| Human immunodeficiency virus 1 | EC50 | = | 95300.0 | nM | 4.02 | Antiviral activity against Immunodeficiency virus type-1 (HIV-1) in peripheral b... | 11052795 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 9301659 | 10.1021/jm9703698 | ADMET | 3 |
| 11052795 | 10.1021/jm990113x | Human immunodeficiency virus 1 | 3 |
| 11052795 | 10.1021/jm990113x | ADMET | 3 |
| 11052795 | 10.1021/jm990113x | CCRF-CEM | 3 |
| 11052795 | 10.1021/jm990113x | Vero | 3 |
| 9301659 | 10.1021/jm9703698 | HepG2 | 1 |
| 9301659 | 10.1021/jm9703698 | CCRF-CEM | 1 |
| 11052795 | 10.1021/jm990113x | Hepatitis B virus | 1 |
Data from ChEMBL 36 via Core Engine