Compound Detail
CHEMBL1275686
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Basic Information
| ChEMBL ID | CHEMBL1275686 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | BONHUVYFXXMJFR-UHFFFAOYSA-N |
1
Targets
1
Activities
1
Assay Types
0
PK Parameters
9
Publications
0
Known Names
Molecular Properties
267.1
MW (Da)
-0.88
ALogP
6
HBA
3
HBD
127.7
PSA (Ų)
0.47
QED
0
Ro5 Violations
5
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 4.11
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| NON-PROTEIN TARGET CHEMBL3879801 | EC50 | 4.11 | 4.11 | 78000.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| NON-PROTEIN TARGET | EC50 | = | 78000.0 | nM | 4.11 | Antiviral activity against Murine cytomegalovirus Smith infected in HFF cells by... | 18852272 |
Literature References
| PubMed | DOI | Target Context | # Activities |
|---|---|---|---|
| 18852272 | 10.1128/aac.00918-08 | Unchecked | 7 |
| 18852272 | 10.1128/aac.00918-08 | NON-PROTEIN TARGET | 5 |
| 18852272 | 10.1128/aac.00918-08 | HFF | 2 |
| 18852272 | 10.1128/aac.00918-08 | Human betaherpesvirus 5 | 1 |
| 18852272 | 10.1128/aac.00918-08 | Human alphaherpesvirus 3 | 1 |
| 18852272 | 10.1128/aac.00918-08 | Human alphaherpesvirus 2 | 1 |
| 18852272 | 10.1128/aac.00918-08 | Human alphaherpesvirus 1 | 1 |
| 18852272 | 10.1128/aac.00918-08 | MOLT-3 | 1 |
| 18852272 | 10.1128/aac.00918-08 | Daudi | 1 |
Data from ChEMBL 36 via Core Engine