Compound Detail
CHEMBL1300243
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Basic Information
| ChEMBL ID | CHEMBL1300243 |
| Phase | Preclinical |
| Structure Type | MOL |
| InChI Key | RHNBLPLXJVTVBI-UHFFFAOYSA-N |
2
Targets
2
Activities
2
Assay Types
0
PK Parameters
0
Publications
0
Known Names
Molecular Properties
221.3
MW (Da)
0.69
ALogP
4
HBA
0
HBD
46.6
PSA (Ų)
0.61
QED
0
Ro5 Violations
1
Rot. Bonds
Drug Information
| Molecule Type | Small molecule |
| Availability | Unknown |
| Chirality | Unknown |
Activity Summary
EC50 1 meas. best 4.84
IC50 1 meas. best 4.63
Target Activity Profile
| Target | Type | Best pChEMBL | Mean pChEMBL | Best (nM) | # Data |
|---|---|---|---|---|---|
| Unchecked CHEMBL612545 | EC50 | 4.84 | 4.84 | 14285.0 | 1 |
| Signal transducer and activator of transcription 3 CHEMBL4026 | IC50 | 4.63 | 4.63 | 23520.0 | 1 |
Activity Data Samples
Top measurements by pChEMBL value
| Target | Type | Rel. | Value | Units | pChEMBL | Assay | PubMed |
|---|---|---|---|---|---|---|---|
| Unchecked | EC50 | = | 14285.0 | nM | 4.84 | PUBCHEM_BIOASSAY: Screen for small molecule probes relevant to Friedreichs ataxi... | - |
| Signal transducer and activator of transcription 3 | IC50 | = | 23520.0 | nM | 4.63 | PUBCHEM_BIOASSAY: Dose response cell-based assay to measure STAT3 activation. (C... | - |
Data from ChEMBL 36 via Core Engine